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News--
WASHINGTON (Reuters) - Regular aspirin users may be
protecting themselves against a form of cancer called Hodgkin's lymphoma as well
as against colon cancer and heart disease, U.S. researchers reported on
Wednesday.
In the latest report to suggest that aspirin has effects that could prevent
cancer, a team at the Harvard School of Public Health found that patients who
took two or more aspirins a week over five years reduced their risk of Hodgkin's
lymphoma, a type of immune system cancer.
Ellen Chang and colleagues questioned 565 patients with Hodgkin's lymphoma
and 679 healthy people about their use of aspirin and related drugs called
non-steroidal anti-inflammatory agents, or NSAIDS.
They found the regular aspirin users were only 60 percent as likely as non
users to be in the cancer group.
To their surprise, they found that regular users of acetaminophen, a
non-aspirin pain reliever, nearly doubled their risk of the cancer -- but said
it may have been because patients started taking the drug to control their
as-yet undiagnosed cancer symptoms.
Chang's team said the findings must be confirmed in bigger studies but said
it could be aspirin actively prevents the immune disruption involved in
Hodgkin's disease.
"Given the extensive inflammation and immune dysregulation accompanying
Hodgkin's lymphoma, an attractive hypothesis is that anti-inflammatory drugs
guard against the onset of disease," they wrote in their report, published in
the Journal of the National Cancer Institute.
"If aspirin use is indeed found to protect against Hodgkin's lymphoma, this
relationship could afford insight into the pathogenesis of the disease and offer
possible clues toward its prevention," they added.
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