The regime -- very similar to the controversial Atkins Diet -- yielded some
encouraging results. By filling up on high-fat foods and cutting out starches
entirely, the heart patients lost an average of 5 percent of their body weight
over the six-week study, according to findings published Nov. 11 in the Mayo
Clinic Proceedings.
What's more, the patients did not see measurable increases in their blood-fat
levels.
Although the researchers say further study is needed, they believe the
results help substantiate the high-fat, low-carb diet made popular by the late
Dr. Robert Atkins.
"Low and behold, we ended up with something very close to what Dr. Atkins had
been saying for years," says Dr. James H. Hays, the endocrinologist and
researcher who led the study at Christiana Care Health Services in Wilmington,
Del.
Recent studies show the Atkins approach is effective for short-term weight
loss. A key question is whether the diet will achieve results over a longer
period of time while avoiding a harmful buildup of artery-clogging fat that
could boost patients' risk for cardiovascular disease.
Hays is heartened by the diet's positive results with two other groups of
patients who were tracked for longer periods of time. They included women with
polycystic ovary syndrome, a hormonal condition, and people with reactive
hypoglycemia, whose blood sugar drops after a meal.
Those with polycystic ovary syndrome lost 14.3 percent of their total body
weight over 24 weeks. Reactive hypoglycemia patients dropped 19.9 percent of
total body weight over a year. Neither group showed any significant change in
blood-fat levels, Hays says.
In an editorial published in the same issue, Dr. Gerald Gau of the Mayo
Clinic's Division of Cardiovascular Diseases expresses concern about the
long-term cardiovascular risk of the diet. Still, he recommends researchers
"keep an open mind regarding the role of the Atkins diet and continue to study
its metabolic effects."
Hays' study focused on a relatively small sample of patients -- just 17 men
and six women with atherosclerotic heart disease. All were obese and had been
treated with cholesterol-lowering medications before entering the trial.
Patients with diabetes were excluded.
Participants were asked to get half their daily calories from saturated fat,
primarily red meat and cheese. Fresh fruit and non-starchy vegetables were
allowed in restricted amounts, but starches were strictly forbidden.
The researchers don't know exactly how many calories patients consumed
because participants were not required to precisely record their fruit and
vegetable intake. The scientists estimate each meal contained at least 600
calories for a total daily intake of 1,800 calories. Almost all of the weight
loss resulted from reduced caloric consumption, they believe.
Overall, the diet resulted in decreases in weight and body fat and
participants kept blood-fat levels in check, the study found.
Not everyone will be persuaded by the results of the study, Hays says. "It's
very small, it's very short and it's uncontrolled," he concedes.
Amy Joy Lanou, nutrition director at the Physicians Committee for Responsible
Medicine, is among the skeptics. "I'd be very interested to see what happens
with these individuals if the study was taken out over a year," she says.
The committee recently called on a U.S. advisory panel to warn the public
about the dangers of high-protein, low-carb diets -- including the risk for
cardiovascular disease -- in its next update of federal dietary guidelines.
Lanou advises people concerned about their weight to consider a diet proven
to be safe and effective over a longer period of time. "We do know that choosing
a plant-based diet will result in better health as well as weight loss," she
says.